Officials say the children ranged in age from 13 to 17. They were found in New Jersey, New York, Connecticut and Pennsylvania.
Some were high school students whose families reported them missing.
More than 50 women who were forced to work as prostitutes were also rescued and more than 45 pimps were arrested.
Officials say many of the pimps forced the women to travel from out of state to the area to work during the Super Bowl.
State, local and federal officials have spent months trying to combat forced prostitution during the Super Bowl, an event they say draws potentially lucrative opportunities for sex traffickers.