Police say a 40-year-old man was found shot in the head along with a 30-year-old woman who had been shot in the chest inside a home at 2624 West Somerset Street just after 2:30 p.m.
Both were pronounced dead at the scene.
Police are searching for a weapon and motive.
Police say five people were taken into custody after a fight broke out among family members.
The incident remains under investigation.