Danny Daneil Diaz, 32, of the 700 block of West Butler Street, is being called a 'person of interest' in the case.
Police say Diaz rented a room from the victim at that location.
Officers were called to the scene around 12:30 a.m. after reports of a man screaming.
The victim said Diaz beat him with a wine bottle.
The victim suffered multiple head and face injuries and was rushed by medics to Temple University Hospital.
There was no immediate word on a motive for the attack.
Diaz is described as a Hispanic Male, 5'7" tall and weighing 185 pounds. Police say he is known to frequent the area of the 200 block of East Indiana Avenue, where a family member lives.
Anyone with information on the whereabouts of Danny Daneil Diaz is asked to contact East Detective Division at 215-686-3243, or dial 911.