It happened Saturday night just after closing time at the Target in the 11000 block of Roosevelt Boulevard in Somerton.
The surveillance video shows each male suspect entering the store separately, each talking on a cell phone as he enters.
The video then shows the armed suspects emerging from the men's bathroom after the 10:00 p.m. closing time and instructing a store employee to open multiple cash registers.
The suspects then methodically empty each register of cash before walking out of the store with hoods pulled up over their heads.
Investigators say the thieves made off with between $10,000 and $30,000 in cash.
The three men were last seen heading toward the Haldeman Manor Apartments in the 10000 block of Haldeman Avenue.
Police released the following description of the suspects:
Suspect #1: Black male, 5'5", dark complexion, wearing glasses, black hooded sweatshirt with "make the dream real" on the front, gray pants, army green sneakers, and armed a handgun.
Suspect #2: Black male, light brown complexion, wearing a gray hooded sweatshirt, dark colored backpack, dark colored pants, and white/gray Air Max sneakers. This suspect changed his gray sweatshirt to a red hooded sweatshirt.
Suspect #3: Black male, dark brown complexion, wearing a dark colored hat, gray hooded sweatshirt with white and red writing, and gray pants.
Anyone with information is urged to contact Philadelphia Police at 215-686-TIPS (8477), text a tip to PPD TIP (773847) or through PhillyPolice.com.