The incident happened on Thursday, March 23, in Chatsworth, Los Angeles.
The video, which has since gone viral, shows the tire detaching from the truck and going underneath what appears to be a dark-colored Kia, sending it flying into the air and flipping it upside down. Debris was scattered across the freeway.
A spokesperson with the California Highway Patrol confirmed the Kia driver suffered minor injuries.
Sheared-off lug nuts apparently led to the pickup truck's tire detachment.