The crash happened just after 1 a.m. Friday in the eastbound lanes of the expressway in Sicklerville, New Jersey.
Police say the driver lost control, went down an embankment and then the vehicle caught fire.
Rescue crews had to pull the driver out. That person suffered 2nd- and 3rd-degree burns and was airlifted to a nearby hospital.
The eastbound lanes were closed in that area overnight, but traffic is now getting by the scene.