It happened just before 4 p.m. Saturday at the Gray Friars Apartments, located on Grays Friars Drive in Chalfont.
Police say a 32-year old man was stabbed inside his apartment.
He was taken to a local hospital where he is listed in serious condition.
Investigators say the man was the intended target, but haven't said what the motive might have been.
Anyone with information should call New Britain police at 215-822-1919.