The victim has been identified as 22-year-old Garret Christino of Highstown, Mercer County.
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It happened around 10:36 p.m. Friday at mile point 2.2 in Carneys Point.
New Jersey State Police said Christino's Nissan Altima had a blown out tire and became disabled in the left lane and left shoulder.
A box truck traveling in the left lane then struck the Nissan.
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Police said Christino died from his injuries.
The driver and passenger in the box truck sustained minor injuries.
The accident remains under investigation.