Officers were called to 9th and Cherry streets in Chinatown at 10:30 p.m. Tuesday for reports of a shooting.
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They found a 23-year-old male shot in the chest lying on the sidewalk. He was taken to Jefferson University Hospital in critical condition.
One witness who is a security guard told police it was a drive-by shooting.
Police said they were told by witnesses the vehicle involved in the shooting made its way onto northbound I-95.
Pennsylvania State Police pulled over the vehicle on I-95 at Cottman Avenue.
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Police say they found the suspected shooter and a gun inside the vehicle.
Detectives believe the victim and shooter knew each other. They are working to determine a motive.
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