Police say a group of men was seen confronting a 52-year-old man as he walked on North 10th Street near Race Street around 5:30 a.m. Saturday.
The video shows the confrontation turn into a street brawl. At one point the suspect pulls out a gun and the victim begins to run away.
But after a few steps he's shot twice and falls to the ground. Police say he was critically injured.
The gunman was among a group of people who left a nearby restaurant before the shooting, police say. That group was seen walking towards 9th and Race streets after the shooting.
Anyone with information is asked to contact Philadelphia police.