The crash happened around 5 a.m. Tuesday in the 200 block of West Crescent Boulevard near the Collingswood Diner.
Police say one person was trapped in one of the vehicles.
It took rescuers 30 minutes to free the victim.
That person was rushed to Cooper University Hospital for treatment. There was no immediate word on the victim's condition.
No other injuries were reported.
Route 130 (Crescent Boulevard) was closed at Route 30 (Whitehorse Pike) as police investigated.
All lanes were back open by 6:15 a.m.
Police were working to determine what led to the crash.