Sproles originally suffered a partial tear of the muscle during the game against the New York Jets on October 6.
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According to the Eagles, Sproles went through four weeks of rehabilitation including a return to practice on October 30.
He was fully cleared after "extensive testing and participation in practice," the Eagles said.
The team said Sproles played in the November 3 game against the Chicago Bears without reporting any issues.
"When the team returned on November 11th, Darren was a full participant in Monday's practice, as well as a workout on Tuesday. Following Wednesday's practice, Darren reported the injury and was evaluated," the Eagles said.
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According to the team, further testing on Thursday revealed the torn hip flexor muscle.
Sproles is a 15-year veteran and three-time Pro Bowler.