It happened on the 500 block of West Luray Street around 10:30 p.m.
Police found the victim, a man in his 20s, with a bullet wound to the head.
He was taken to Temple University Hospital where he was pronounced dead.
Witnesses told police that the suspect was driving a PT Cruiser.
Officers found 5 shell casings on the street.
If you have any information you are asked to contact police.