It happened around 3:30 a.m. on Rayland Road near Keswick Road.
Investigators said a person who lived inside an apartment at that location called 911 to report a home invasion.
They said someone entered the apartment and made off with a Rolex watch and 5 guns.
Police said the suspect ran from the scene. Officers are searching for a man who was reported to be wearing all black at the time of the incident.
There were no injuries reported.
Anyone with information is asked to contact the police.