It happened after 10 p.m. Thursday at Courtland and Boudinot streets.
Police say the two victims were sitting in the vehicle when someone approached them and opened fire on the passenger side.
A 24-year-old man was shot in the leg, and a 22-year-old woman was shot in the back.
Both victims were rushed to Temple University Hospital in stable condition
It is not clear if the two were targeted.
So far, no arrests or word on a motive.