It happened inside a house on the 1800 block of East Clementine Street just before 4 am.
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Police say two men were shot in the head inside a second-floor bedroom.
They say the victims are in their late teens or early 20s and did not have identification on them.
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Both victims were taken to Temple University Hospital.
Investigators don't know the motive but tell us the location is a known drug house.
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