According to police, the shooing happened in the 1000 block of Appletree Street at about 3 a.m.
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The victim suffered life-threatening injuries, police said.
Witnesses said the victim and the suspect in the shooting were involved in a dispute earlier in the night after leaving a club nearby on Arch Street.
Detectives are now reviewing surveillance footage in the search for the shooter.
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Anyone with information is asked to call police.
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