It happened on Dunsmore Road in Newark at around 11 p.m. Sunday.
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Police say the 55-year-old male victim was shot in the back while driving.
He continued on for about three blocks before crashing onto the sidewalk.
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The victim was rushed to the hospital in critical condition.
Police have not said whether the victim was the intended target or had been struck by a stray bullet.
They were checking the scene for any other shell casings to pinpoint where the bullets were fired.