The department said in a news release that officers, along with state and federal law enforcers, raided the home on Friday.
Authorities say police found a laboratory and components to manufacture methamphetamine.
Thirty-six-year-old David Loder; 36-year-old Vivian Loder and 50-year-old Clark Rholetter are all charged with operation of a clandestine lab and conspiracy. Twenty-five-year-old Gordon Clark was charged with possession of drug paraphernalia.