According to police, the accident occurred just after 6 a.m. Sunday near mile post 3.1 on Mays Landing Road/State Highway 73.
The accident occurred when the driver of a Chevy Impala crossed into the northbound lanes while traveling southbound, and struck a Ford Escape head on.
The drivers of both vehicles were transported to the hospital with serious injuries.
The driver of the Impala was identified as 28-year-old Edwin Velez of Vineland. The driver of the Escape was identified as 21-year-old Sonia Lopez-Martinez of Vineland.
The highway has since been reopened.
The accident remains under investigation.
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