Tiffany Moore was southbound on Route 55 in Deptford Township when she left the highway around 9:15 p.m. Tuesday.
The 26-year-old Glassboro woman - who wasn't wearing a seat belt - was ejected from the vehicle and was pronounced dead at the scene a short time later.
Moore was traveling by herself when the crash occurred. Authorities say no other vehicles were involved.
The accident forced authorities to shut down a stretch of the highway for several hours, causing some traffic delays.
The cause of the crash remains under investigation.