Caleb Wood scored 18 points, Darnell Foreman had 16, AJ Brodeur added 11, and Max Rothschild scored nine points with 10 rebounds for the Quakers (22-8, 12-2).
The Quakers hit 11 of 18 3-pointers (61.1 percent) and shot 56.1 percent from the field to sweep the season series.
After leading 47-31 at halftime, Antonio Woods' layup put Penn up 58-40 and the Quakers led by 22 on Jackson Donahue's 3 with 11:14 to go. Tamenang Choh scored 11 straight for Brown and the Bears closed to 97-93 on Jason Massey's 3 with two seconds left before Betley iced it with two free throws.
Choh and Brandon Anderson scored 23 apiece and Desmond Cambridge added 16 for Brown (11-16, 4-10), which has lost six straight. It was a season high for Choh, a freshman.
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