The fire started before 9 p.m. in a 4-story brick, partially occupied by apartments on the 300 block of North Church Street.
Firefighters say the blaze went to three alarms, and it was necessary for a swift evacuation.
The blaze was quickly placed under control.
One firefighter and a juvenile were taken to an area hospital to be evaluated for non-life threatening injuries.
So far, there is no word on what caused the blaze.
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