Gregory Leiber, 57, died after the incident around 9:15 a.m.
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According to investigators, the Langhorne, Pa. man was driving on I-276 eastbound just past the Norristown exit in Whitemarsh Township.
State police say a truck driving in the westbound lanes struck debris on the roadway, sending it over the concrete barrier.
RAW VIDEO: Fatal crash on Pa. Turnpike
That debris hit Leiber in the head, killing him.
Video from Chopper 6 showed a black vehicle stopped at the scene with a hole in the windshield.
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Police say they are trying to find the truck that hit the debris as the investigation continues.
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