It happened at 10:55 a.m. Thursday in the southbound lanes just south of I-76 in Lower Merion Township.
Video from Chopper 6 HD showed a dark-colored SUV lying on its roof and a red Volkswagen Beetle with heavy rear-end damage.
Chopper 6 over Lower Merion crash
Action News is told two of the injured were taken Bryn Mawr Hospital, one was taken to Paoli Hospital, and one was taken to Lankenau Hospital.
There was no immediate word on the extent of injuries to the victims.
Traffic was backed up on I-476 South approaching the scene. A secondary backup was visible on westbound I-76 approaching the Blue Route.
Stay with Action News and 6abc.com for more information as it becomes available.
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