The crash happened after the driver of a 2006 Chevrolet truck exited I-495 at Edgemoor Road but crashed on Governor Printz Boulevard.
Police say they initially attempted to pull over the driver for traffic violations on I-95 near mile marker 9.0.
Chopper 6 over crash in Delaware following police pursuit
A Maryland woman was arrested and charged with fleeing and eluding. She has not been identified.