It happened around 2:30 a.m. on Monday, July 25 on South 2nd Street between Walnut and Chestnut.
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According to the U.S. Park Rangers of Independence National Historical Park, four male suspects assaulted two people in the parking garage.
Further details on the attack have not been released.
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Authorities say security cameras captured images of the wanted suspects.
Anyone with information is asked to call 888-653-0009 or 911.
"You don't have to tell us who you are, but please tell us what you know," the National Park Services said.