It happened around 1:45 p.m. at the Wells Fargo branch located at 2005 Market Street.
Police said a man presented a demand note to a teller and after receiving an undetermined amount of cash, he fled the bank and remains at large.
The man is described as a clean-shaven black man in his early 30s to 40s, roughly 5 feet 8 inches tall. At the time of the incident he was wearing a red hooded sweatshirt and tan work pants.
No injuries have been reported.
Video from the scene of a Center City bank robbery Friday
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