Police in the area of the 2200 block of West Berks Street heard gunshots around 8 p.m. Thursday.
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When officers arrived at the scene, they found a 33-year-old male victim in the front passenger seat of a Ford SUV suffering from multiple gunshot wounds.
He was taken to Temple University Hospital where he died of his injuries.
The victim has been identified as Ignacio Rodriguez who lived on the same block.
Investigators learned the victim was working at the family's variety store nearby.
After Rodriguez and other family members closed the store for the night at 8 p.m., he walked to the parked SUV.
As Rodriguez was entering the front passenger seat, police say someone in a sedan traveling eastbound on Berks Street fired several shots striking the victim and the parked vehicle.
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Rodriguez was struck in the head, chest and torso.
Police believe he was the intended target.
They say cameras captured the incident.
Investigators are continuing to search for the shooter.