It happened just before 10 p.m. on the 5000 block of Griscom Street.
The flames were showing from the rear of a three-story apartment upon arrival to the scene.
The fire was quickly knocked down, but one person died in the blaze. The victim has not been identified.
A police officer was also taken to an area hospital for smoke inhalation.
Stay with Action News as we continue to follow this developing story.