The incident occurred in the southbound lanes near the exit ramp for the Walt Whitman bridge just after 11 p.m. Friday.
The 26-year-old victim was riding at a high rate of speed when he lost control and hit a guardrail.
The victim was taken to Hahnemann Hospital where he was pronounced dead.
Police shut down the highway to just one lane as they investigated.
The scene was cleared around 3 a.m. Saturday.
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