The daughter of Rep. Mike O'Brien said he died in the early hours on Monday in the home where he had lived as a child in the city's Fishtown neighborhood.
Bridget O'Brien says her father had been battling a host of medical issues.
The 64-year-old O'Brien had decided not to seek re-election this year. He had been the ranking Democrat on the Urban Affairs Committee.
Survivors also include his wife and son.
Mike O'Brien had been a legislative aide to his predecessor, and before that had worked in a meatpacking plant.
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