It happened at a store near 54th Street and Wyalusing Avenue.
Police say a man in his 20s entered the store wearing a ski mask with intentions on committing a robbery.
That's when he was shot one time in the abdomen by the store owner.
Police found a man fitting the suspect's description behind the wheel of a Pontiac nearby.
He was rushed to the hospital where he later died.
The store owner was not hurt.
Police: Store owner shoots would-be robber in West Philadelphia