Investigators say the 43-year-old victim was stabbed in the neck either inside or outside of the home on the 3100 block of North Stillman Street around 1:30 a.m. Wednesday.
A 1-year-old and a 2-year-old were in the house at the time, but were not injured.
Police say the man did not live at the home.
They do not have a description of the suspect.
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