Chopper 6 was overhead as the FBI could be seen focused on a residence on the 5900 block of Woodbine Avenue.
"The FBI is in that area conducting court-authorized law enforcement activity. As it relates to an ongoing matter, we're not able to provide further comment at this time," said an FBI spokesperson in a statement to Action News.
Further details on the investigation have not been released at this time.
Feds close off Philly neighborhood due to investigation
Neighbors say the feds arrived early Friday morning.
"It was pandemonium all around," recalled one resident. "Had the undercovers, the FBI, the SWAT, guns, they wouldn't even allow anyone to walk up the street."
Three people were taken away in handcuffs, according to those who live on the block.
"I heard them say, 'We have a warrant, come out.' After a while, the guy came out and they brought him out in his underwear," recalled the resident.
The focus on this particular home is shocking for many neighbors who say that at least four people live at the home and they've lived there for a while.
Stay with Action News as we continue to follow this developing story.