It happened around 5:15 a.m. Friday at Wayne Avenue and West Rittenhouse Street.
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The police cruiser smashed into a no turn on red sign at the intersection. It had severe front-end damage.
A second vehicle stopped on a front lawn about 10 feet away.
Several city blocks were cordoned off during the response.
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The condition of the officer in the cruiser has not been released.
No other injuries have been reported.
It is not clear at this time what led to the crash.