The incident began Thursday just after 12:30 p.m. on the 3100 block of N. Bancroft Street.
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Authorities say plainclothes officers observed a 23-year-old man wanted for a homicide go into a home along the residential block.
Officials declared the incident a barricade just after 1 p.m., and SWAT is staged in the area of 17th Street and Allegheny Avenue.
Police have not identified the suspect nor have they provided any further information about the case.
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The home was cleared around 5 p.m. The suspect is still being sought at this time.