Two of those men are in critical condition after being shot multiple times.
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Gunfire erupted on the 1300 block of Luzerne Street shortly after 4 p.m.
Police say a large group of people was standing at the corner when a black Chevrolet Tahoe with two shooters inside opened fire.
A 39-year-old man was taken to the hospital by private vehicle where he was placed in critical but stable condition. That private vehicle then left the hospital, police say.
A 20-year-old man who was shot nine times is also hospitalized in critical condition. Police say that victim is the son of a Philadelphia police department civilian employee.
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An 18-year-old man was shot in the bicep, while a 37-year-old man was shot in the foot. Both of those victims are hospitalized in stable condition.
The gunmen fled the scene. Police say they found at least 27 spent shell casings from two separate guns.
"This is an area frequented by a lot of people, couple of businesses here... hopefully we're going to be able to get more information on what happened," Insepctor DF Pace said.
No arrests have been made at this time.
Police are scrubbing through surveillance video to get a better look at the vehicle's tag, and the shooters.
There was no word on a motive for this shooting.
No arrests have been made.