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The multi-vehicle crash involving an overturned vehicle happened around 4:30 a.m., shutting down all lanes of I-76 EB approaching Girard Avenue.
Two people were injured. Their conditions have not been released.
On Sky 6 cameras, drivers could be seen going the wrong way down a ramp; some even turned around on the Schuylkill Expressway itself.
All lanes were reopened around 5:20 a.m.
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