The shooting happened at C and Somerset streets around 10:25 p.m. Monday.
Philadelphia police say they are interviewing a person of interest, as well as the woman who was in the passenger's seat at the time of the shooting. She was not hurt.
The 33-year-old driver was taken to the hospital in critical condition.
Officers found a rifle in the front seat with the pair. It's unclear who it belongs to or if anyone fired it during the confrontation.
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