Gunfire rang out near 17th Street and Chelten Avenue shortly after 9:30 p.m. Wednesday.
Police said a 25-year-old man was shot multiple times. He was taken to the hospital in critical condition.
A 23-year-old woman was also shot twice in leg and is in stable condition.
Police said there was a baby with the victims, but the child was not hurt.
Officers recovered a gun at the scene.
The suspect was taken into custody after the crash near Broad and Olney streets