A large paper recycling plant on 49th Street near Grays Avenue went up in flames, reaching three alarms just before 6:30 p.m.
Plumes of smoke billowed from the burning building.
"This is crazy. There are like three different fires happening at once," said Kori Beaman of Southwest Philadelphia. "I can't imagine how many people it is going to take to put that out."
It took firefighters almost three hours to tame the blaze.
No injuries have been reported.
An investigation into the cause of the fire continues.
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