Police say just after 9 p.m. Saturday night, they were in pursuit of a stolen Cadillac Escalade.
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While eluding police, the stolen car crashed into two vehicles and struck a man in a wheelchair at Aramingo and Castor avenues.
The 38-year-old man in the wheelchair was taken to the hospital where he was later pronounced dead.
A 27-year-old woman and an 11-year-old child were inside one of the vehicles involved in the crash.
They were taken to the hospital with non-life-threatening injuries.
The four people in the stolen vehicle fled the scene.
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Chief Inspector D.F. Pace told Action News, "Three ran in one direction, and the fourth occupant ran in another direction. The officer gave chase to the fourth individual who he saw throwing bullets from his pockets..."
Officers were able to catch the fourth suspect, who has since been identified as 19-year-old Efrain Rosario from the 4300 block of Porter Street. He is charged with two gun-related offenses.
Police recovered three loaded guns inside the Cadillac.
The other three suspects, believed to be in their late teens, remain on the run.
Anyone with information on this case is asked to call police at 215-686-TIPS.