The crash happened around 6:30 a.m. Saturday on West Springfield Road.
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Police say the motorcycle was traveling at a high rate of speed before the crash.
The bike crossed the center lines and struck the car head-on.
The impact projected the motorcycle driver over the car, and onto the SEPTA 101 tracks, temporarily halting service.
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That driver died at the scene.
The female driver of the car was not injured.
The crash remains under investigation.