The fire broke out just before 4:30 p.m. Friday in the 3100 block of West Dauphin Street.
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Upon arrival, officials said heavy fire was showing from the second floor of a two-story residence.
The fire was brought under control just before 5 p.m., officials said.
The injured person was taken to Temple University Hospital. No word on their condition.
The cause of the fire has not been determined.