It happened around 6:25 p.m. Tuesday on the 3000 block of North Marshall Street.
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Police say the girl was struck in the thigh.
A 31-year-old man was shot in the ankle. A 21-year-old man was shot in the neck.
The adults were taken to Temple University Hospital with the 21-year-old in critical condition.
The girl was taken to St. Christopher's Hospital for Children.
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Both she and the 31-year-old man are in stable condition.
Police say they have recovered a weapon.
No arrests have been made.