Police say at 11:50 p.m. last Saturday, 25-year-old Maya Young was found on the 4800 block of Penn Street with multiple stab wounds to the neck and chest.
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She was taken to Aria Health Frankford where she was pronounced dead a short time later.
Following an investigation, police arrested 24-year-old Tiffany Floyd and 19-year-old Jose Pena.
Floyd was taken into custody on Tuesday, Pena on Wednesday.
They have both been charged with Murder and Conspiracy.