It happened around 6 p.m. Sunday near the intersection of Route 29 and Plan Road in Perkiomen Township, Pennsylvania.
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Police say the kids were riding their bikes along Route 29 when they were both hit by a car.
One victim was flown to St. Christopher's Hospital for Children.
The other victim was flown to Lehigh Valley Hospital in Allentown.
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No word on their conditions at this time.
The driver did stay on the scene, police say.
Police are investigating.