Police were called to the 4400 block of North Cleveland Street just after 3 a.m. Sunday.
Police say when they arrived at the scene they found a man shot in the chest.
He was taken to the hospital in critical condition.
Authorities say a second victim later arrived at the hospital, with a gunshot wound to the foot.
He is in stable condition.
Detectives recovered 18 rifle shells from the scene.
So far, no arrests have been made.