It happened around 5 a.m. Monday after the Street Road exit.
Investigators say a Ford Fusion struck a barrier, leading to a crash involving two other vehicles.
The driver of the Fusion, a 65-year-old man from Levittown, was pronounced dead at the scene. His name has not yet been released.
All northbound lanes were shut down for more than four hours as crews responded.
The cause of the crash remains under investigation.
For the latest conditions on area highways, check 6abc.com/Traffic.